2020 BAD Meeting

June 11^th 2020 – 4^th Boston Area Drosophila Meeting | Boston University

Virtual Meeting due to the COVID-19 pandemic.

LOCAL ORGANIZERS
Kim McCall | Prof. & Chair of Biology, Boston University
Nelson Lau | Assoc. Prof., Boston University School of Medicine

AGENDA

12:30 PM – 12:35 PM	Welcoming Remarks Kim McCall, Horacio Frydman, the BADM Committee
12:35 PM – 1:30 PM	Vertical transmission of Wolbachia in Drosophila gut cells and its effects in stem cell division Natalie Vaisman, Frydman lab, Boston University – – – – – – – – – – – – – – – – – – – – – – – – – – – – – – – – – – – – – – – – Zombiflied: Interrogating the mechanistic basis of behavior manipulation using the “zombie” entomopathogen Entomophthora muscae Carolyn Elya, de Biovort Lab, Harvard University – – – – – – – – – – – – – – – – – – – – – – – – – – – – – – – – – – – – – – – – Two peptides encoded from a single transcript regulate mitochondrial function in Drosophila Justin Bosch, Perrimon Lab, Harvard Medical School – – – – – – – – – – – – – – – – – – – – – – – – – – – – – – – – – – – – – – – – Investigation of variant PRC1 complexes in Drosophila Janel Cabrera, Emmanuel College – – – – – – – – – – – – – – – – – – – – – – – – – – – – – – – – – – – – – – – – Wound-induced polyploidization: an adaptive healing strategy Vicki Losick, Boston College
1:30 PM – 1:35 PM	BREAK
1:35 PM – 2:35 PM	Role of the Circular RNA Edis in Innate Immunity and Neurodevelopment Rui Zhou, Johns Hopkins All Children’s Hospital – – – – – – – – – – – – – – – – – – – – – – – – – – – – – – – – – – – – – – – – Defining a critical glial role for Parkinson’s disease risk genes in controlling alpha-synuclein toxicity Abby Olsen, Feany Lab, Harvard Medical School – – – – – – – – – – – – – – – – – – – – – – – – – – – – – – – – – – – – – – – – Operant Conditioning to a Food Reward Requires Rest Timothy Wiggin, Griffith Lab, Brandeis University – – – – – – – – – – – – – – – – – – – – – – – – – – – – – – – – – – – – – – – – Flexible cross-inhibition controls Drosophila larva thermotaxis Luis Hernandez, Samuel Lab, Harvard University – – – – – – – – – – – – – – – – – – – – – – – – – – – – – – – – – – – – – – – – Internal state configures olfactory behavior and early sensory processing in Drosophila larvae Katrin Vogt, Samuel Lab, Harvard University – – – – – – – – – – – – – – – – – – – – – – – – – – – – – – – – – – – – – – – – Open bar assay: A reward self-administration paradigm for studying drug and substance use disorders John Hernandez, Kaun Lab, Brown University
1:35 PM – 2:35 PM	Regulation of epidermal cell differentiation by the Hippo pathway and Bonus Heya Zhao, Veraksa Lab, University of Massachusetts – Boston – – – – – – – – – – – – – – – – – – – – – – – – – – – – – – – – – – – – – – – – Modeling Genomic Complexity of Colorectal Cancer using Multi-genic Drosophila Models Sindhura Gopinath, Cagan Lab, Mt. Sinai – – – – – – – – – – – – – – – – – – – – – – – – – – – – – – – – – – – – – – – – An auto-inhibitory clamp of actin assembly promotes synaptic endocytosis Steven Del Signore, Rodal Lab, Brandeis University – – – – – – – – – – – – – – – – – – – – – – – – – – – – – – – – – – – – – – – – Nuclear receptor Ftz-f1 promotes follicle maturation and ovulation partly via bHLH/PAS transcription factor Sim Jianjun Sun, University of Connecticut – – – – – – – – – – – – – – – – – – – – – – – – – – – – – – – – – – – – – – – – The Ecdysone response pathway differentially regulates the Hippo pathway in two subtypes of post-mitotic photoreceptors Joseph Bunker, Rister Lab, University of Massachusetts – Boston – – – – – – – – – – – – – – – – – – – – – – – – – – – – – – – – – – – – – – – – Dietary Stress Affects Structure and Function of the Eye Khanh Lam-Kamath, Rister Lab, University of Massachusetts – Boston
1:35 PM – 2:35 PM	Investigating the relationship between genome organization of paired chromosomes and genome function at the single cell level in Drosophila Jumana AlHaj Abed, Wu Lab, Harvard Medical School – – – – – – – – – – – – – – – – – – – – – – – – – – – – – – – – – – – – – – – – Regulatory mutations play the major role in the evolution of gene activity David Loehlin, Williams College – – – – – – – – – – – – – – – – – – – – – – – – – – – – – – – – – – – – – – – – De novo evolved genes are essential for Drosophila male fertility and act at multiple stages of spermatogenesis Geoff Findlay, College of the Holy Cross – – – – – – – – – – – – – – – – – – – – – – – – – – – – – – – – – – – – – – – – Transcriptional changes in Drosophila genome during vitamin A deprivation Deepshe Dewett, Rister Lab, University of Massachusetts – Boston – – – – – – – – – – – – – – – – – – – – – – – – – – – – – – – – – – – – – – – – Aging leads to changes in transposable element landscapes in Drosophila Nachen Yang, Lau Lab, Boston University – – – – – – – – – – – – – – – – – – – – – – – – – – – – – – – – – – – – – – – – Har-P, a short P-element variant, weaponizes P-transposase to severely impair Drosophila development Nelson Lau, Boston University
2:35 PM – 2:55 PM	BREAK
2:55 PM – 3:25 PM	Neurobiology & Behavior Paul Garrity, Professor at Brandeis University, Discussion Leader – – – – – – – – – – – – – – – – – – – – – – – – – – – – – – – – – – – – – – – – CRISPR & Other Tools Stephanie Mohr, Director of DRSC/TRiP-FGR at Harvard Medical School, Discussion Leader – – – – – – – – – – – – – – – – – – – – – – – – – – – – – – – – – – – – – – – – Human Disease Modeling & Metabolism Marla Tipping, Assistant Professor at Providence College, Discussion Leader – – – – – – – – – – – – – – – – – – – – – – – – – – – – – – – – – – – – – – – – Gene Regulation & Epigenetics Jens Rister, Assistant Professor at University of Massachusetts – Boston, Discussion Leader – – – – – – – – – – – – – – – – – – – – – – – – – – – – – – – – – – – – – – – – Stem Cells & Development Kristin White, Associate Professor at MGH/Harvard Medical School, Discussion Leader – – – – – – – – – – – – – – – – – – – – – – – – – – – – – – – – – – – – – – – – Diversity & Science in a Pandemic Michelle Markstein, Assistant Professor at University of Massachusetts – Amherst, Discussion Leader
3:30 PM – 4:15 PM	KEYNOTE – Germ cells are forever Dr. Ruth Lehmann, Laura and Isaac Perlmutter Professor of Cell Biology, New York University; Incoming Director of the Whitehead Institute, Massachusetts Institute of Technology
4:15 PM – 5:30 PM	A non-canonical odor receptor mediates responses to the widely attractive odor ammonia Karen Menuz, University of Connecticut – – – – – – – – – – – – – – – – – – – – – – – – – – – – – – – – – – – – – – – – Sleep loss can cause death through accumulation of reactive oxygen species in the gut Yosef Kaplan Dor, Rogulja Lab, Harvard Medical School – – – – – – – – – – – – – – – – – – – – – – – – – – – – – – – – – – – – – – – – Persistent Calcium Spikes Are an Axon Injury Signal Controlling Subtype-specific Regeneration Fei Wang, Xiang Lab, University of Massachusetts Medical School – – – – – – – – – – – – – – – – – – – – – – – – – – – – – – – – – – – – – – – – “Disease-relevant” to disease model: how FlyBase can help you investigate human disease in Drosophila Victoria Jenkins, FlyBase – – – – – – – – – – – – – – – – – – – – – – – – – – – – – – – – – – – – – – – – A flexible new platform for insect cell biology: pooled genome-wide CRISPR screens Raghuvir Viswanatha, Harvard Medical School – – – – – – – – – – – – – – – – – – – – – – – – – – – – – – – – – – – – – – – – Online Bioinformatics Resources from the DRSC/TRiP Claire Hu, Director of Bioinformatics, DRSC/TRiP-FGR, Harvard Medical School – – – – – – – – – – – – – – – – – – – – – – – – – – – – – – – – – – – – – – – – Large-scale transgenic Drosophila resource collections for loss- and gain-of-function studies Jonathan Zirin, Director of in vivo Technologies, DRSC/TRiP-FGR,  Harvard Medical School
5:40 PM	Closing Remarks Nelson Lau, the BADM Committee